For each user database rebuild indexes, update statistics and shrink. The script will use the system catalog to produce a list of databases. If you want to excluce a database add the excluded db name to the 'not in' list. You can also adjust the target fillfactor.
Indexes, Indexes, Indexes
This article has a description of an index utilization tool that Ron Johnson uses to analyze the effectiveness and use of indexes in a system.
2012-07-04 (first published: 2011-07-05)