Which columns do i need to verify for checking less usage of indexes from below query

SELECT * FROM sys.dm_db_index_usage_stats

This is the table which stores an Order of 93 columns, And this DB is design develop 10 years ago.

Hi,

Thanks all of you, for your valuable suggestions. Below i am providing the estimation size of different tables with index also which resides on single file i.e. Primary.... may be...