ANSWER: Yes

Caveat: Unless you don't need to enable FILESTREAM for fle I/O streaming access

The Server service (Lanman Server in Registry) handles functions associated with the Windows share, e.g., SQLEXPRESSLOCAL. ...

Grant Fritchey (1/12/2011)

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If you go into configuration manager for the instance in question and open the properties for that instance, you can't enable FILESTREAM on the appropriate tab? It sounds...