There is a lot of places to look actually. Controller Selection and -Layout for the Disks matters as much as seeing that the VM can pass QD > 1 to the SAN, provisioning ratio, even the interconnect between host and storage array matters if for nothing else than latency.
As you said yourself it's an open ended Question and I think to get hints about issues that only seem to occur when virtualized, this is the wrong forum after all. There is a good reason why the VMware Certification track goes to such extend because it's not done in 5 minutes and all runs well. There is also a whitepaper on the Webs for SQL Server on VMware best practices, maybe you should consult that first.
Don't get me wrong I don't want to sound harsh but I've been part of one team with a VMware Infrastructure where in the end of the story VMware did release ESXi 6.5 Update 1 because of the issues we faced and couldn't even get to see a PSOD. Not even VMware did want to belive there was no PSOD until they were on site having a look at it themselves.