Generally, not possible.
You can query sys.dm_db_index_usage_stats per database and check the dates in there, but that's only since the last time the DB was started (typically last time SQL Server starts), but that's about it unless you have some form of auditing or tracing set up.
Gail Shaw
Microsoft Certified Master: SQL Server, MVP, M.Sc (Comp Sci)
SQL In The Wild: Discussions on DB performance with occasional diversions into recoverability
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