Something like this is likely to work
use master
kill 75 -- the connection to the database in single user mode
use [MyDatabase]
alter database [MyDatabase] set multi_user with rollback immediate
If that doesn't work, try this:
use master
kill 75 -- the connection to the database in single user mode
alter database [MyDatabase] set offline with rollback immediate
alter database [MyDatabase] set online, multi_user with rollback immediate
Another thing you could do is disable the logins that have access to the database, kill the active database connection, and then alter the database.