Yep. 100%. I've run it from Apple, Linux and, of course, Windows. Except for the small sections of it that still require Silverlight, it works fine on any OS with any browser that I've tried.
"The credit belongs to the man who is actually in the arena, whose face is marred by dust and sweat and blood"
- Theodore Roosevelt
Author of:
SQL Server Execution Plans
SQL Server Query Performance Tuning