I know that Microsoft made some improvements to the patching process in SQK 2008, but this is so long ago I cannot remember the exact details.
It is always worth taking a backup image of OS and SQL program files and the system databases before applying a patch, so that you can safely revert to the pre-patch situation if a problem arises. Also, it is best to apply patches to non-production machines followed by regression testing before applying that patch to production, as this gives you the opportunity to not apply a patch to a business-critical server.
Original author: SQL Server FineBuild 1-click install and best practice configuration of SQL Server 2017 2016, 2014, 2012, 2008 R2, 2008 and 2005. 1 Dec 2016
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Disclaimer: All information provided is a personal opinion that may not match reality.
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