CheckDB is an online operation. Users may note slow down, but that's all.
Better question, if your database becomes corrupt, how soon do you want to find out about it and how long do you retain your backups?
If you do find corruption, restore from backup should always be an option and that means doing integrity checks often enough that restore from a clean backup is always possible
Microsoft Certified Master: SQL Server, MVP, M.Sc (Comp Sci)SQL In The Wild
: Discussions on DB performance with occasional diversions into recoverability
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