If I understand correctly, it can make all the difference or no difference at all. Each option has its own deploy destination. If you set up each option with different configuration settings (different destination server, path, etc.) then when you select an option and then deploy it will deploy to the selected destination. If however, you work in a small environment and don't really have practical options for alternate deployment for testing or whatever, or if you are just lazy and don't bother configuring all the options it doesn't make a difference either.