We're saying that having all the columns in the index, as key or include, is a very bad idea. Does the index really, really, really need to be that large? Is that need sufficient to justify using double (or more) the space of the table itself in total? Does it justify the costs of rebuilding an index that large and maintaining and index that large?

I can't tell you whether you should or shouldn't remove those includes without seeing the queries that run against that table. Do some investigation, look at all the queries that run against that table. Which ones use that index? Will they still use it if it's smaller?