- AWE is not needed for 64bit OS, it's only a window for 32bit OS to address more memory

- As mentioned, enable 'lock pages in memory' on 64bit OS

- If you have multiple instances, make sure you set the minimum and maximum memory for each instance. If you don't do this, instances will battle for memory under high pressure.

- You can prioritize instances by using processor and/or IO affinity

- make sure you have some free memory available for OS etc. Monitor ' Memory Paging' for this issue.

- As a general rule, my servers have a minimum of 1 GB free memory.