Good question, and a learning experience for me
I missed it too, not realizing that the underscore wouldn't catch 'C_us'. The lesson learned is that underscore as a wildcard means that there MUST be some character, but % will accept the absence of a character. Proved this out by modifying your question a touch.
create table #Like_Test( Col1 varchar(5) )
go
insert #Like_Test values('_Cu')
insert #Like_Test values('_Cus')
insert #Like_Test values('Cus_')
insert #Like_Test values('C_us')
insert #Like_Test values('Cus')
insert #Like_Test values('Cu_s')
select * from #Like_Test
where Col1 Like '%Cu_%'
select * from #Like_Test
where Col1 Like '%Cu%'
select * from #Like_Test
where Col1 Like '%C%u%'
drop table #like_test
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