I've used both Red Gate and LiteSpeed products. As far as compression and speed, they are pretty much the same. LiteSpeed product has far more bells and whistles to go along with it, much of them I never touch. LiteSpeed is the only Cluster aware product. It's also far more expensive. I'd go with Red Gate if it's only for compression and speed, but if you have any other needs you might as well get the best product available - LiteSpeed.