You seem to be looking for cases with more than 1 address alias, which can be detected by having a comma (",") in the alias column.
So maybe this will work:
SELECT nr
, case when alias not like '%,%' then NULL else [address] end
, case when alias not like '%,%' then NULL else alias end
from @info
That's not very efficient, but your info table isn't even in 1st normal form and efficiency is not going to happen when you start off with a table which is disastrously deficient in normalisation.
Tom