I'm very particular with how my desktop is set up but the desk it sits on is usually a mess

Dual monitors when I can although I find myself working from home via VPN/RDP way too often.

A fast desktop computer with gobs of ram. I have had some embarrassingly slow computers and finally after many years of complaining, got an upgrade at work.

SSMS/SSIS 2008R2/2012

Text Editors:

EditPlus for looking at large text file

LTFViewr5U when I have to look at really large text files

Notepad ++

UltraEdit

DbVisualizer I got it to look at large schemas but end keeping it open to monitor a few of my problematic servers

SSDT-VS 2012. What a great and free tool from Microsoft. Started using it for schema compares but am finding myself working with it as a SQL editor as well

Recent Microsoft Office. Running 2013 on work, laptop, home desktop and work now.

PowerShell

VMware vSphere at work and Hyper-V on Windows 8 at home