Pick a column in your table and create a persisted computed column off it using the HASHBYTES function:

ALTER TABLE dbo.[TableName]

ADD [HashedColumnName] AS CAST(HASHBYTES('MD5',CAST([ExistingColumnName] AS VARCHAR(40))) AS VARBINARY(40))

PERSISTED -- important, computed column must be persisted to be used a partition column

Creating Partitioned Tables and Indexes