Running profiler means you are capturing the information related to specific database / activity. For that SERVER has to collect the details and any activity on the server affect CPU/Memory/IO etc.
That is the reason if you need accurate data of load of your database/server you need to run the profiler from the other machine however that will increase the network traffic.
HTH
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"Thare are only 10 types of people in the world:
Those who understand binary, and those who don't."