Avamar Version 7.2.1.32 w/Avtar
SQL Server 2008 R2 & 2012 Enterprise Versions

I realize this is an old thread, but after reading several posts I felt compelled to chime in on our experiences with this product if for nothing else then to vent a little.

1. Doesn't handle multiple backup requests on the same instance.  This is particularly an issue if you have multiple instances on a single server (clusters, 2008 R2/2012, etc...).  For example, if you run a backup on Instance A, then try to run a backup on Instance B while Instance A is still running Instance B will fail.
2. Other backup processes affect performance.  For example, we replicate backups from our primary local Avamar server to a DR facility with a second Avamar server.  Replication runs for 18-19 hours and never completes.  What is worst, when replication, tape backups, or any other type of non-SQL backup is running, it negatively affects the backup/restore times of my SQL backups with Avamar to the data domain.
3.  Speed difference between Native and Avtar with Avamar is negligible.  None of our databases are large, nothing over 500GB.  When other processes are running on Avamar, backup times are longer than Native.
4.  My experiences with EMC support for this product have been dismal & depressing.  There only seem to be one or two guys who know their stuff but finally obtaining one of them is difficult and typically very time consuming.

I have other complaints, those are my top 4.  My recommendation would be to stay away from this product if at all possible.