Please make sure if you have configured memory settings for SSRS in RSReportServer.config file.
For example(sample values only):
<MemorySafetyMargin>80</MemorySafetyMargin>
<MemoryThreshold>90</MemoryThreshold>
<WorkingSetMaximum>4000000</WorkingSetMaximum>
<WorkingSetMinimum>2400000</WorkingSetMinimum>
Refer to https://msdn.microsoft.com/en-us/library/ms159206.aspx
R