look at this.... although this only reads, I'm sure there is a registry method to write to the registry as well. I would take a backup of the registry before I'd go poking my fingers around in there as well as make sure I'd do this in a sandbox area too.
http://www.databasejournal.com/features/mssql/article.php/3764516
[EDIT] upon further digging...here is a script fragment...
$protocolproperty=Get-WmiObject -namespace root\Microsoft\SqlServer\ComputerManagement -class ClientNetworkProtocolProperty ` -filter "PropertyName='Default Port'" $protocolproperty.SetNumericalValue(7001)
this came from the same site I mentioned above but different article...
http://www.databasejournal.com/features/mssql/article.php/3709441
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