Nuclear has its challenges, but it's the only proven technology that could handle the kind of power generation that we need for the next 100 years until other alternates take over.
There are only two challenges, both worthy of consideration.
1) What to do with spent fuel? The French have been recycling fuel effectively for the last 30 years. Because spent fuel is a recognized challenge, we're developing better and better ways to recycle.
2) Meltdown. Pretty serious. Again (and I'm not usually a big fan of the French) the French have been running their reactors safely for a long time.
We've learned how to build and operate nuclear plants safely for the long haul, and concerns that might have been legitimate 30 years ago no longer apply now. It's the only legitimate way to go at the moment. Solar and wind are great, but we need something that will produce power when the wind stops blowing and he sun goes down.
“Politicians are like diapers. They both need changing regularly and for the same reason.”