not directly, no.
each column has to be referenced in the update statement, but you can use the schema tables to generate the SQL statement for you.
you were a little loose on the details...a decimal point replaced in a varchar is different than a decimal point in a decimal/float datatype...do you mean find and replace a '.', or turna value into an integer?
what is a full stop that you want to replace? a CrLF?
here's a simple example to generate an update for every VARCHAR field in a given table:
declare @vbCrLf CHAR(2)
SET @vbCrLf=CHAR(13) + CHAR(10)
SELECT
max(s3.create_date) AS create_date,
s3.name As [TheTable],'UPDATE ' + s3.name + ' SET ' +
stuff(( SELECT ',' + name + ' = REPLACE(' + name + ',''badstring'',''goodstring)' + @vbCrLf
FROM sys.columns s2
WHERE OBJECT_NAME(s2.object_id)= s3.name --- must match GROUP BY below
and TYPE_NAME(s2.system_type_id) = 'varchar'
ORDER BY s2.column_id
FOR XML PATH('')
),1,1,'') as [TheColumns]
FROM sys.columns s1
inner join sys.objects s3 on s1.object_id = s3.object_id
WHERE s3.type='U'
GROUP BY s3.name --- without GROUP BY multiple rows are returned
ORDER BY s3.name
Lowell