• Start with this two-part series. Finding the problem is more than half the battle.

    http://www.simple-talk.com/sql/performance/finding-the-causes-of-poor-performance-in-sql-server,-part-1/

    I doubt there's a single, comprehensive site that covers everything. The links given earlier are good but that's far from everything. Read blogs, articles and performance questions here. Grant Fritchey's book (link in his sig) is a very good resource.

    Gail Shaw
    Microsoft Certified Master: SQL Server, MVP, M.Sc (Comp Sci)
    SQL In The Wild: Discussions on DB performance with occasional diversions into recoverability

    We walk in the dark places no others will enter
    We stand on the bridge and no one may pass