In addition to Gert's blog, Barclay Hill is posting on best practices with VSTS:DBE. It's worth a read. http://blogs.msdn.com/bahill/default.aspx
"The credit belongs to the man who is actually in the arena, whose face is marred by dust and sweat and blood"
- Theodore Roosevelt
Author of:
SQL Server Execution Plans
SQL Server Query Performance Tuning