Realizing that fragmentation is an inevitability, we allocate time each night for a complete run of DBCC DBREINDEX on each database. Of course, as servers fill and client requests increase, the maintenance windows shrink (what a shame) so continuing this practice may become rather difficult, forcing a switch to a 1x a week schedule or something.

There is a gold lining though. As a couple others have mentioned, it is possible to do a complete defrag (logical and physical) whole the databases are online. Most "modern" tools such as D.K. allow this.

We've recently upgraded to tthe latest version of this tool and find it not only very effective at defragging tasks but much more efficient than expected. As always, I would suggest plenty of development testing befiore using on your production servers but to date, we've had no issues in any of our environments. There is a 30 day free trial. Use it!