1- Check Eventviewer
2- Check disk free space
3- Try login with SQLCMD using [sysadmin] windows login or sa if it works
4- Read database Error Log, what is going on the server.
5- Check history to see what is changed/modified or ran over last moments.
There is a list going on. See if this helps to have some clue on issue and you can resolve.
Shamshad Ali