I think a mini-series based on Arthur C. Clarke's four "Rendezvous with Rama" novels would be interesting, so long as it's not a low budget Syfy Channel job, and if they plan it out properly to conclude from beginning to end in a single season.
http://en.wikipedia.org/wiki/Rendezvous_with_Rama
"Do not seek to follow in the footsteps of the wise. Instead, seek what they sought." - Matsuo Basho