That helps clarify. I wouldn't use MERGE for this. I converted your sample ddl into temp tables so it is easier to work with in a test database.
create table #SourceTable
(number int)
create table #DestinationTable
(number int)
insert into #SourceTable values(1)
insert into #SourceTable values(2)
insert into #SourceTable values(3)
insert into #SourceTable values(4)
insert into #SourceTable values(5)
insert into #SourceTable values(6)
insert into #DestinationTable values(1)
insert into #DestinationTable values(2)
insert into #DestinationTable values(3)
select *
from #SourceTable
where number not in
(
select number
from #DestinationTable
)
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