so once I set the backup drive and change my default paths, AND move my master, model and MSDB data and log files, I will still have files in the following folders??

F:\MSSQLxx_xx.MSSQLSERVER\MSSQL\FTData

F:\MSSQLxx_xx.MSSQLSERVER\MSSQL\Log

and I still have no idea what to do with the MS_AgentSigningCertificate file in the F:\MSSQLxx_xx.MSSQLSERVER\MSSQL\data directory??

ultimately, I want to be able to drop the entire F:\MSSQLxx_xx.MSSQLSERVER\MSSQL folder structure and really clean it up.

just seems easier to me to re-install, I just don't know if the simple act of uninstalling SQL Server will release the drives that I assigned to this Instance back to the cluster as available.