nested replace would probably be the easiest:;
you could substring it as well, because the desired string, including dashes will be 36 chars.
SELECT REPLACE(REPLACE('{784A4579-8689-438E-ADAA-9DCBC8A88AE7}','{',''),'}',''),
SUBSTRING('{784A4579-8689-438E-ADAA-9DCBC8A88AE7}',2,36)
Lowell
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