One way to do it is before doing the datapump task to load data to the workbook, set up an ActiveScript task.
Then, do some VBScript to
open Excel
open the workbook
select the right worksheet
select the ActiveRange
delete the ActiveRange.
Save the workbook
close Excel
Sorry I don't have the code off the top of my head right now, but you should be able to find some VBScript examples to do the bulk of it. Just google for it w/o specifying DTS, maybe something like: "VBScript Excel"