In all the years of using MSSQL (since 7), I have never encountered a situation where auto-creation of statistics has had to be disabled.
I have. however, encountered several situations where auto-update has failed due to the relevant table sizes, where we have scheduled a job to manually update stats on a regular basis (usually every 3 days)
Space, the final frontier? not any more...
All limits henceforth are self-imposed.
“libera tute vulgaris ex”