My home lab in on a HP Microserver, with ESXi installed then a few VMs. Haven't had any issues.

Before I got myself thee Microserver, I used to run OracleBox[/url] on my machine. Again, no complaints apart from "guru meditation mode" on errors.

I user Hyper-V on my work desktop, which is my preference when running the VMs on the same machine I'm working on.